Providing-world class operational expertise, logistical infrastructure, and the scientific rigor needed to effectively characterize, research, and treat infectious diseases as they emerge.

Vaccine Development

We deploy an expert global team who can utilize their experience, knowledge, and the best technologies available to accelerate clinical trials to ultimately reduce the burden of infectious disease. We do this empowered by our people, science, and technology and infrastructure.

Throughout the years Cerba Research established an impressive track record by supporting studies in all phases of vaccine development, with innovative pre-clinical models and customized clinical models. A wide range of assays are available to test vaccine safety, efficacy, immune toxicology and pharma kinetics.

The latest integrated laboratory techniques allow for high-through put analysis. Our assay portfolio includes:

Best-in-class molecular assays: Quantitative Real Time PCR (qPCR), digital droplet PCR (ddPCR) and next-generation sequencing (NGS)

Whole exome sequencing, whole genome sequencing, single cell sequencing, RNA sequencing, microbiome and metagenome
Immune Repertoire Sequencing (IRS)
State-of-the-art immunological and ligand-binding assays, including antibody and cell mediated immunity assays (ELISA, ELLA, MSD, ELISpot assays, neutralizing antibodies (nAbs) and more) here
Novel research techniques including our in-house developed ViroSpot™
High quality serology
Numerous safety testings such as hematology, biochemistry, coagulation, urinalysis, pregnancy test, lipase, amylase, thyroid function, serum calprotectin, anti-IFN alpha-2, and more
Flow cytometry with our globally harmonized BD FACS Canto, BD FACS Lyric and Cytek Aurora instruments
Collection and processing of peripheral blood mononuclear cells (PBMCs) available in 45+ laboratories from 25+ countries here
Biomarker analysis and immunoprofing with our multiplex and simplex immunohistochemistry (IHC) 250+ protocols
NanoString®, FISH, ISH, and more

your partner in vaccine development

At Cerba Research, we offer a vast array of virology / immunology and molecular diagnostic assays for your vaccines research and development. We can carry out the necessary laboratory analysis of clinical samples and analyze the results on your behalf, reporting these results back to you in formats that comply with regulatory authority requirements, such as, but not limited to, the U.S. Food & Drug Administration (FDA) and the European Medicines Agency (EMA).

With extensive experience in analyzing complex datasets, including next-generation sequencing, we are proud to offer customized solutions to streamline and enhance your data reporting process for your vaccines research and development.

Through extensive collaboration with diagnostics and biopharmaceutical companies, we can help enhance your clinical vaccines development.

Experience With Relevant Viral Diseases

We have distinct experience with viral targets such as:

Human papillomavirus (HPV)
Hepatitis viruses (HBV and HCV)
HIV
Herpesviruses (CMV, EBV, VZV, HSV)
Respiratory infections (RSV, Rhinovirus and Influenza virus)
Polio
SARS-CoV
SARS-CoV-2

And other targets, including:

Rabies
MERS
Hmpv
Dengue
Chickungunya
VZV

A unique footprint in South Africa

Our South African facilities and capabilities have been established for over 25 years. With offices in Durban, Cape Town, and Johannesburg, we are uniquely positioned to respond to emerging trends in infectious disease, on the African continent.  Collaborating with government health agencies, non-profit (NPHOs), and clinical research organizations (CROs) from routine testing to specialized testing includes:

Safety Laboratory
PBMC Processing
Speciality Molecular Testing
Tuberculosis P3 Laboratory
Biobanking Facility

Our People

Our global team has extensive infectious disease experience with dedicated project management capabilities. We pride ourselves on being client-focused, proactive and transparent with scientist to scientist communication. We work hard to understand your challenges and tailor solutions to your scientific questions.

Science

Our scientific capabilities are vast. They cover, but are not limited to., speciality testing cutting edge assay development, virology and molecular testing. pre-clinical including invitro/animal modelling NGS Molecular diagnostics and molecular biology, and technology transfer of assays. We also offer a full suite of virology, immunology, molecular and customized assays and have a track record in influenza, SARS-CoV-2, RSV, HBV, Polio, HPV, CMV serology microbiome analysis, and cell-mediated immunity assay including flow cytometry with intracellular cytokine staining.

Logistics & Process

Our logistics and processes support spans BSL3 & BSL2 facilities, GAP III compliant polio facilities, our network of processing Labs across 5 continents USA, and biobanking and biospecimen solutions to facilitate IVD registration and assay development. We also have the largest global PBMC & processing laboratory network with state of the art processing, ensuring the highest–quality expertise in building bespoke virology test kits and providing training to end users

Infectious Disease Highlights

We’re part of operation Warp Speed NIH contract and have supported not for profit organisations & government vaccine trials conducted by the Africa CEPI Alliance.