PBMC & BMMC - Cerba Research

The usefulness and efficiency of PBMC studies should not be overlooked. The increased use of these immune mononuclear cells as a promising indicator of drug efficacy in clinical trials as well as the increased convenience of working with samples versus conducting testing makes PBMCs crucial. At Cerba Research we embrace the potential of PBMC activities to maximize impact in clinical research.

To keep up with rising clinical research demand we perform various PBMC activities like isolation from whole blood samples and DNA extraction using advanced technologies and equipment.

PBMC isolation on a global scale
Harmonized SOP/QC and instrumentation
Utilize Density Grade Centrifugation (DCG) with CPT® tubes
For use in immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, personalized medicine, and toxicology.

At Cerba Research, we can also efficiently isolate BMMCs for your clinical trials. We have done so on numerous occasions, mostly for hematological malignancy trials.

Harmonized SOPs on a global scale for PBMCs isolation, cryopreservation, and storage ensuring high viability and recovery

Viability ≥97%

Post collection using CPTtubes , the average viability obtained is 99.3% after 4 hrs, 97.9% after 24 hrs, and 96.8% and 85.5% respectively post-thawing

Recovery ≥75%

After thawing the average recovery is 75%

Premium Logistics

Management of sample processing labs
PBMC personnel training program and certification
Custom sampling kits preparation
Sample tracking and tracing (e.g. guaranteeing a temperature-controlled supply chain and online-sample timelines)
Premium courier transportation in accordance with ADR & IATA regulations

High Quality Standards

All our pre-processing labs are accredited to the relevant local laboratory accreditation standards, which include: CAP, GCP, GLP, ISO17025/15189
Quality control and personnel trainings are monitored on-site to ensure compliance with the processing procedures required by the customer

Extensive Network

45+ processing labs in America, Europe, Africa, Asia, and Australia
Ability to on-board lab partners worldwide
Processing labs in 25+ countries

Standardized SOPs

Our standard PBMC processing protocol includes Vacutainer® CPT mononuclear cell preparation tube
Customized upon request short turnaround times
Same-day PBMC isolation (Turnaround times may vary from one country to another, reflecting possible transportation delays or excessive workloads within the lab.)

Research & Partner labs

Pre-Processing labs

Office locations and Technical Platforms

Download more information here

Brochure – Processing Peripheral Blood Mononuclear Cells (PBMC) For Clinical Trials

White paper – Decoding a TCR and BCR Fingerprint – Immune Repertoire Sequencing

Reach out to our experts and see how we can help advance your clinical trial

Processing Peripheral Blood Mononuclear Cells (PBMCs) And Bone Marrow Mononuclear Cells (BMMCs) For Clinical Trials