Our Genomic Services for Infectious Diseases
Our service unit has been structured in a way that allows for efficient handling of both small batches of individual samples and large sets of samples required for clinical trials.
We offer molecular virology, bacteriology, and pathology diagnostic solutions using a broad range of cutting-edge equipment.
Broad bacterial screening can be performed using various singleplex or multiplex real-time PCR-based assays, detecting infectious diseases such as:
● Haemophilus influenza
● Moraxella catarrhalis
● Mycoplasma pneumoniae
● Legionella spec
● Pseudomonas aeruginosa
● Streptococcus pneumoniae
● Staphylococcus aureus
● Streptococcus pyogene
Cerba Research Genomic Capabilities For Infectious Diseases
We are your trusted partner for your Genomic needs in Infectious Diseases
Microbiome
The 16S rRNA gene is present in all bacterial genomes and demonstrates considerable sequence diversity among different bacteria, enabling characterization of complex microbial communities at the genus level. Its nine hypervariable regions (I.e., V1 to V9) exhibit variable degrees of sequence diversity among different bacterial genera.
We offer amplification of the V1-V2, V3-V4 or V4 region (depending on the sample type) and sequencing on an Illumina sequencing platform. The generated reads are classified using a the well-known QIIME II pipeline combined with the Silva reference database, resulting in community profiles, alpha diversity (diversity within a sample) and beta diversity (diversity between samples).
Whole Genome Sequencing
Besides microbiome analysis, Cerba Research also offer whole genome sequence analysis of isolated bacterial strains. These whole genome data can be used for epidemiological purposes (e.g., MRSA outbreaks) or to support the clinical development of targeted anti-bacterial therapies.
Genomic DNA of cultured bacterial strains can be sequenced on an Illumina sequencing platform (short reads) or combined with sequencing on an Oxford Nanopore Technology platform (long-reads). Reports can include de novo (short) or hybrid (combined) assembly, phylogenetics and AMR prediction.
Reach out to our genomics team and see how we can help advance your research