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Case Study – Multiple Myeloma efficacy and safety of 2 different combination therapies

Discover how our team of experts performed a multicenter, randomized, open-label study to compare the efficacy and safety of two different combination therapies in subjects with refractory or relapsed and refractory multiple myeloma.

The main challenge was the quality and volume of bone marrow samples, and the streamlining of the testing flow for downstream applications on isolated cells with limited volume formed challenges for in-house scientists and sponsor.

Having clear communication with the sites on sampling techniques allowed for the maximization of bone marrow draws. The assay was successfully transferred to other sites (USA), and the reporting for protein electrophoresis was standardized.

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