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Retrospective Biomarker Analysis Performed To Measure Tumor-infiltrating CD39+ CD8+ T Cells in Metastatic Renal Cell Carcinoma

A biotech conducted a phase II study to analyze the percent expression of CD8+ mRCC tumor samples. This secondary endpoint was done by means of IHC simplex method and chromogenic detection through Cerba Research labs.

After garnering CD8+ data, there was a strong scientific interest in retrospectively assessing tumor-infiltrating CD39+ CD8+ in mRCC. Of note, high tumor-infiltrating CD39+ CD8+T cells may indicate poor prognosis in RCC.

Discover how our scientists rose to the challenge and assist the biotech to realize its phase II study.